Organizations working to create positive social, environmental, and health impact now have access to several outstanding funding opportunities designed to strengthen their programs, expand their reach, and improve sustainability. Whether you are a nonprofit, civil society organization, community-based organization (CBO), social enterprise, or healthcare institution, these grants provide financial resources, strategic partnerships, and capacity-building support to help maximize your impact.
This article highlights four major grant opportunities currently available for organizations across Africa, Sub-Saharan Africa, low- and middle-income countries, and other eligible regions. These opportunities are offered by respected international organizations committed to supporting locally led development, social innovation, environmental protection, and healthcare quality improvement.
The funding opportunities featured include:
- Oak Foundation Multi-Year Grants
- New Africa Fund Matching Grants
- Segal Family Foundation Partnership Funding
- ISQua Quality Improvement Grants
Below is everything you need to know about each opportunity.
1. Oak Foundation Multi-Year Grants (Rolling Applications)
The Oak Foundation provides substantial multi-year grants to nonprofit organizations and civil society organizations working to achieve long-term social and environmental change.
Unlike many grant programs, organizations do not necessarily need to receive an invitation before expressing their interest. Eligible organizations whose work aligns closely with the Foundation’s priorities may submit an unsolicited Letter of Inquiry (LOI) for consideration.
Oak Foundation is known for supporting initiatives that create sustainable, systemic, and long-lasting impact rather than short-term interventions.
Funding Available
Organizations may receive:
- Average grant size of approximately USD $900,000
- Funding awards of up to USD $10 million for exceptional initiatives
The Foundation primarily supports organizations capable of delivering significant impact in areas aligned with its funding priorities.
Who Can Apply?
Eligible applicants include:
- Nonprofit organizations
- Civil society organizations
Applicants should demonstrate strong alignment with the Oak Foundation’s funding priorities.
Deadline
Rolling applications (No fixed deadline)
Organizations may submit a Letter of Inquiry throughout the year.
2. New Africa Fund Matching Grants
The New Africa Fund is supporting early-stage organizations across Africa by providing financial assistance together with organizational development support.
The initiative aims to strengthen the long-term sustainability of African organizations by combining matching grants with fiscal sponsorship and capacity-building opportunities.
Funding Available
Successful organizations may receive:
- Up to USD $5,000 in matching funds
Additional Benefits
Selected organizations will also benefit from:
- Twelve (12) months of free fiscal sponsorship
- Capacity-building opportunities
- Access to organizational development support
- Opportunity for top-performing organizations to attend an intensive workshop in Kigali, Rwanda
These additional services are designed to help organizations strengthen governance, fundraising capacity, and operational sustainability.
Eligible Applicants
Applications are welcomed from:
- Non-governmental organizations (NGOs)
- Community-Based Organizations (CBOs)
- Social enterprises
Organizations must be located within one of the 55 African Union Member States.
Deadline
14 August 2026
Applicants are encouraged to submit their applications before the deadline.
3. Segal Family Foundation Partnership Funding
The Segal Family Foundation supports locally led organizations that are driving sustainable development across Sub-Saharan Africa.
Rather than operating through a traditional open grant competition, the Foundation builds long-term partnerships with organizations demonstrating exceptional impact and leadership.
Its funding approach emphasizes trust-based philanthropy by providing flexible, unrestricted support that allows organizations to invest where resources are most needed.
Funding Support
Partner organizations receive:
- Flexible unrestricted funding
- Long-term strategic partnership
- Organizational strengthening support
- Capacity development
- Relationship-based collaboration
Because the funding is unrestricted, organizations have greater flexibility to allocate resources according to their strategic priorities.
Who Can Apply?
The Foundation works with:
- High-impact organizations
- Locally led development organizations
- Organizations operating across Sub-Saharan Africa
Application Process
There is no open call for applications.
Instead, new partners are identified through trusted referral networks and strategic recommendations.
Organizations interested in learning more can review the Foundation’s partnership approach through its official website.
4. ISQua Quality Improvement Grant
The International Society for Quality in Health Care (ISQua) is inviting applications from organizations committed to improving healthcare quality and patient safety in low- and middle-income countries.
The grant supports initiatives that strengthen healthcare systems and improve the delivery of safe, high-quality healthcare services.
Funding Available
Successful applicants may receive:
- €15,000
Eligible Organizations
The grant is open to:
- Healthcare organizations
- Hospitals
- Professional associations
- Health-focused NGOs
Applicants should be based in low- and middle-income countries (LMICs).
Deadline
12 August 2026
Interested organizations should complete their applications before the closing date.
Comparison of the Four Funding Opportunities
| Opportunity | Funding | Eligible Applicants | Deadline |
| Oak Foundation | Average USD $900,000 (up to USD $10 million) | Nonprofits and civil society organizations | Rolling |
| New Africa Fund | Up to USD $5,000 + fiscal sponsorship | NGOs, CBOs, Social Enterprises in Africa | 14 August 2026 |
| Segal Family Foundation | Flexible unrestricted funding | High-impact organizations in Sub-Saharan Africa | No open call |
| ISQua | €15,000 | Healthcare organizations and health NGOs in LMICs | 12 August 2026 |
Why Organizations Should Consider These Opportunities
Each of these funding opportunities supports organizations seeking to increase their impact while strengthening institutional capacity.
Depending on your organization’s mission, these opportunities can provide:
- Significant grant funding
- Flexible unrestricted financial support
- Long-term strategic partnerships
- Capacity-building opportunities
- Fiscal sponsorship
- Professional networking
- Healthcare quality improvement funding
- Organizational sustainability support
- Access to international development partners
Whether your organization focuses on education, health, community development, environmental protection, social innovation, or entrepreneurship, one of these opportunities may align with your goals.
Organizations are encouraged to carefully review the eligibility requirements and application procedures for each fund and prepare strong proposals well in advance of the applicable deadlines.
Learn More
- For more information about this opportunity, Click here
- More global Grant opportunities for youth, visit the OFY website: Click here
