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U.S. Department of State Launches Up to $60 Million Funding Opportunity to Strengthen Uganda’s Health System Through the Health Foreign Assistance MOU Implementation Plan

Grace Amo
U.S. Department of State Launches Up to $60 Million Funding Opportunity to Strengthen Uganda’s Health System Through the Health Foreign Assistance MOU Implementation Plan
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The U.S. Department of State, through its Bureau of Global Health Security and Diplomacy (GHSD), has announced a major funding opportunity under the Advancing Global Health Annual Program Statement (APS) aimed at supporting the implementation of the Health Foreign Assistance Memorandum of Understanding (MOU) between the United States Government and the Government of Uganda.

With up to $60 million in available funding and up to 15 anticipated awards, this initiative seeks to accelerate Uganda’s transition toward a sustainable, accountable, and government-led health system capable of maintaining and expanding gains in public health outcomes.

Organizations with the expertise, capacity, and commitment to strengthening health systems are invited to submit Statements of Interest (SOIs) for projects that align with the priorities outlined in the Uganda MOU Implementation Plan.

Funding Overview

Funding Opportunity Details

Important Deadlines

Applicants are encouraged to carefully review all program guidance and amendment documents before submitting questions or applications.

Why This Funding Opportunity Matters

Uganda is currently implementing a transformative five-year health transition framework covering the period from April 2026 through December 2030.

The framework is designed to:

The initiative supports Uganda’s efforts to maintain progress in:

A key feature of the MOU is the gradual transition from donor-driven implementation models toward government-led and performance-based programming, enabling Uganda to take greater ownership of its healthcare future.

Key Areas of Investment

The Department of State is seeking innovative and capable partners to support two major implementation tracks.

Track 1: Sustainable Faith- and Community-Based Health Systems

Faith-based and community-based health facilities play a critical role in Uganda’s healthcare landscape.

These institutions contribute significantly to:

However, many remain dependent on externally funded projects.

This funding opportunity aims to help these institutions become financially sustainable and operationally resilient.

Objective 1: Establish and Scale Sustainable Community-Based Health Financing Mechanisms

Organizations may propose initiatives that create sustainable financing models capable of reducing dependence on donor funding.

Potential activities include:

Community Health Insurance Development

Income Generation and Revenue Diversification

Organizations are encouraged to:

Equitable Access

Projects should also:

Objective 2: Sustain Integrated Service Delivery in Faith- and Community-Based Facilities

Recipients will help ensure uninterrupted delivery of critical health services during the transition period.

Priority service areas include:

Expected activities include:

Integrated Care Models

Strengthening Health Facility Systems

Support may include:

Workforce Development

Organizations may support:

Objective 3: Build Faith- and Community-Based Organization Capacity

Applicants may focus on strengthening institutional capacity across health facility networks.

Potential interventions include:

Organizational Capacity Building

Revenue Diversification

Projects may support:

Transition Planning

Organizations will be expected to develop plans that gradually shift operational costs toward domestic funding sources.

Track 2: Enabling Systems for Accountable, Government-Led Programming

This track focuses on strengthening the systems required to support Uganda’s transition to performance-based and government-led health programming.

Objective 4: Strengthen and Scale Digital Health Systems

Applicants may support the deployment, integration, and transfer of national digital health systems to government ownership.

Systems include:

Projects should ensure:

Objective 5: Expand Sustainable Power Solutions for Health Facilities

Organizations may support the installation and maintenance of sustainable energy solutions for up to 700 health facilities by 2029.

Potential interventions include:

All technology solutions should be supported by lifecycle cost analysis and coordinated with relevant government authorities.

Objective 6: Institutionalize Supply Chain Accountability and GS-1 Traceability

The Department seeks support for modernizing Uganda’s health supply chain.

Activities may include:

GS-1 Implementation

Digital Integration

Annual Supply Chain Audits

Recipients may conduct audits covering:

  1. Procurement and contract management
  2. Warehousing and inventory management
  3. Distribution and transportation
  4. Data quality and information systems

Objective 7: District-Level Risk Assessments and Performance Verification

Applicants may support:

Government Readiness Assessments

Risk Mitigation Planning

Organizations will help local authorities:

Independent Verification

Recipients may conduct:

Objective 8: Indoor Residual Spraying (IRS) Quality Assurance

Projects may focus on malaria prevention through quality assurance support for Indoor Residual Spraying programs across 35 districts.

Key responsibilities may include:

The goal is to verify:

Guiding Principles for Applicants

All proposed projects should align with the Department of State’s guiding principles, including:

Sustainability and Country Ownership

Projects should:

Protection of Essential Services

Programs must safeguard:

Data-Driven Accountability

Projects should:

Integrated Service Delivery

Applicants should prioritize:

Local Partnerships

Organizations should collaborate with:

Evidence-Based Programming

Activities must be informed by:

Application Process

The funding opportunity uses a two-stage application process.

Step 1: Submit a Statement of Interest (SOI)

Organizations must submit a concise SOI outlining:

Step 2: Invitation for Full Proposal

Selected applicants may be invited to submit a full proposal for further consideration.

Interested organizations may submit SOIs addressing one or multiple objectives.

Apply Here 

Final Thoughts

This significant investment represents one of the most ambitious efforts to strengthen Uganda’s health systems while advancing long-term country ownership and sustainability. Organizations with expertise in health systems strengthening, digital health, supply chain management, health financing, governance, community health, and public health service delivery have a unique opportunity to contribute to Uganda’s transition toward a resilient, accountable, and government-led health system.

With up to $60 million in funding available, successful applicants will play a critical role in supporting healthcare transformation, improving service delivery, strengthening epidemic preparedness, and ensuring that health gains are sustained for generations to come.

For more information on this grant opportunity visit here

For more grant opportunities on OFY, click here 

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